Atf2 myeloid
WebApr 15, 2010 · Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. This Perspective summarizes the emerging role of the transcription factor ATF2 ... WebIn this study, we show two novel points that ATF2 is re-quired for the induction of granulocytic differentiation and associates with granulocyte-specific transcription factor …
Atf2 myeloid
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WebFeb 17, 2024 · The injury-response of myeloid cells in the CNS is thus compartmentalized, adjusted to the type of injury and may represent a therapeutic target. ... Li, M. et al. TRAF6-p38/JNK-ATF2 axis promotes ... WebJan 27, 2024 · In contrast, myeloid colony formation was significantly enhanced on administration of CCL5 (Figures 7D and S7I). These findings reveal that CCL5 treatment is sufficient to rescue the myeloid differentiation in Batf2 KO mice. Collectively, the results suggest that BATF2 promotes myeloid differentiation through activation of CCL5.
WebAcute myeloid leukemia. ATF2. Activating transcription factor 2. AT-MSC. Adipose tissue-derived mesenchymal stem/stromal cell. BAD. Bcl-2-associated death promoter. … WebApr 4, 2024 · National Center for Biotechnology Information
WebDec 19, 2013 · ATF2 regulated cell cycle-related protein expression and inhibited apoptosis in selenite-treated NB4 cells. (a) ATF2 bound to the promoters of cyclin D3, cyclin A and CDK4. A ChIP assay was ... WebDiscover Atf2's significant phenotypes, expression, images, histopathology and more. Data for gene Atf2 is all freely available for download. Cite IMPC; Help; ... Aplastic anemia, Myeloid leukemia, Myelodys... OMIM:614172: Bleeding Disorder, Platelet-Type, 16: Impaired platelet aggregation, Macrothrombocytopenia, Giant platelets, Platelet ...
WebDec 19, 2013 · ATF2 regulates cell cycle-related protein expression. JNK has an important role in modulating cell cycle progression. ATF2, a transcription factor, has also been …
WebAtf2(Δ8,9)-driven tumors show enhanced pigmentation, immune infiltration, and metastatic propensity. Similar to mouse Atf2(Δ8,9), we have identified a transcriptionally inactive human ATF2 splice variant 5 (ATF2(SV5)) that enhances the growth and migration capacity of cultured melanoma cells and immortalized melanocytes. nawab shah alam khan coll of engg and techWebThe gene atf2 is located at human chromosome 2q32. The protein ATF-2 has 505 amino acids. Studies in mice indicate a role for ATF-2 in the development of nervous system and the skeleton. ATF-2 is normally activated in response to signals that converge on stress-activated protein kinases p38 and JNK. marks point public school facebookWebMar 21, 2024 · BATF2 (Basic Leucine Zipper ATF-Like Transcription Factor 2) is a Protein Coding gene. Diseases associated with BATF2 include Hepatocellular Carcinoma . Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding . An important paralog of this gene is … marks plasticsWebWe further demonstrated that LPS stimulated ATF2 and p300 phosphorylation and complex formation via a c-Src/NADPH oxidase/ROS/p38 MAPK pathway. Up-regulation of VCAM-1 led to enhancing monocyte adhesion to HRMCs challenged with LPS, which was inhibited by siRNAs of c-Src, p47phox, p38 MAPK, ATF2, and p300 or pretreatment with an anti … marks point bowling club nswWebSep 21, 2024 · Acute myelogenous leukemia (AML) is a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute myelogenous leukemia denotes the disease's rapid progression. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood … marks place eaton rapids michiganWebOct 15, 2009 · Request PDF JNK1/c-Jun and p38α MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure to Taiwan cobra phospholipase A 2 ... mark spoonamore md uscWebNov 16, 2024 · Activating transcription factor-2 (ATF2), a member of the leucine zipper family of DNA binding proteins, has been implicated as a tumour suppressor in breast cancer. However, its exact role in breast cancer endocrine resistance is still unclear. We have previously shown that silencing of ATF2 leads to a loss in the growth-inhibitory … mark spooner photography