WebDescription. 1. Goniothalamin enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K (m) and k (cat) of the Hsp90s. 2. Goniothalamin induces … WebDec 21, 2012 · Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-deoxygoniopypyrone (7), pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds were identified by spectroscopic analysis …
Emerging Anticancer Potentials of Goniothalamin and Its
WebGoniothalamin is a biologically active styrylpyrone derivative isolated from various Goniothalamus species. The ability of goniothalamin to induce apoptosis via caspase-3 activation against hepatoblastoma (HepG2) and normal liver cells (Chang cells) was studied using morphological and biochemical ev … WebAug 9, 2014 · Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines. In this study, we have elucidated the role of Seladin-1 in goniothalamin-induced cytotoxicity towards human urinary bladder cancer cell line RT4. Methods: The cytotoxicity of goniothalamin in human urinary bladder cancer cell line … guisborough baths
Goniothalamin enhances the ATPase activity of the molecular chaperone
WebGoniothalamicin C35H64O7 CID 44593503 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebOct 1, 2024 · Endoplasmic reticulum stress is one of the pathways involved in cell cytotoxicity. In this study, goniothalamin, one of styryllactone compounds found in plant Goniothalamus spp., was observed to trigger ER stress in HeLa cell line.In addition, we demonstrated that peroxisomal multifunctional enzyme type2 (MFE2) was a specific … guisborough bbc weather