Poly rc binding protein 4

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August undefined, 2024

WebData support the conclusion that poly(rC) binding protein(s) mediate the stability of poliovirus mRNA by binding to the 5'-terminal cloverleaf structure of pol Giovirus mRNA. The 5'-terminal 88 nt of poliovirus RNA fold into a cloverleaf RNA structure and form ribonucleoprotein complexes with poly(rC) binding proteins (PCBPs; AV Gamarnik, R … WebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2), a 39 kDa protein, is a member of the α-globin mRNP stability complex [7, 8]. As a generally known RNA-binding protein, PCBP2 possesses three K homology domains, which are the main RNA-recognition regions [9, 10].

Suppression of Poly(rC)-Binding Protein 4 (PCBP4) reduced …

Webinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein 3CD pro. The formation of the ternary complex is essential for RNA replication and, hence, viral proliferation. PCBP also interacts with stem-loop IV of the IRES, WebPCBP2 knockdown promotes ferroptosis in malignant mesothelioma. PCBP2 might play important roles in central nervous system pathophysiology after spinal cord injury. that the change of poly (C)-binding proteins protein expression was associated with Schwann cell proliferation after the trauma of the peripheral nervous system. grapetree university

Poly a binding protein Sigma-Aldrich

WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … WebOct 16, 2008 · Europe PMC is an archive of life sciences journal literature. Recombinant hnRNP K-homology (KH) domains 1 and 3 of the poly(rC)-binding protein (PCBP) 2 were purified and assayed for interaction with coxsackievirus B3 RNA in electrophoretic mobility shift assays using in vitro transcribed RNAs which represent signal structures of the 5' … grapetree weekly time sheet

Multilevel regulation and molecular mechanism of poly (rC)‐binding …

Advances in poly(rC)-binding protein 2: Structure, molecular …

WebPoly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene. Function. The protein encoded by this gene appears to be multifunctional. It along with … WebMar 21, 2016 · PCBP4 (Poly(RC) Binding Protein 4) is a Protein Coding gene. Diseases associated with PCBP4 include Maxillary Cancer and Jaw Cancer.Among its related … grapetree wholesaleWebFeb 26, 2024 · Small hairpin RNA-mediated depletion of PCBP2 dramatically decreased the viability of gastric cancer cells. Cyclin-dependent kinase 2 (CDK2) was positively regulated by PCBP2 via a direct 3′ UTR binding pathway as determined using a ribonucleoprotein immunoprecipitation assay and a biotin pulldown assay. CDK2 mediated the promoting … grapetree wimborne

"WebSep 22, 2024 · The first pair studied was the protein pair avidin and Biotin. Avidin is a protein typically found in the egg whites while Biotin is a B vitamin. The large protein avidin, can … " - Poly rc binding protein 4

Poly rc binding protein 4

Identification of poly(rC) binding protein 2 (PCBP2) as a target ...

WebDec 8, 2024 · PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the … WebSynonym(s): Anti-Poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations SDS; AV40943: polyclonal: WB: rabbit, human: 1: Expand. …

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Webinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein … WebThe poly(rC)-binding proteins are a subfamily of KH-domain-containing RNA-binding proteins that bind C-rich pyrimidine tracts and play pivotal roles in a broad spectrum of …

WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products Services ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations ... WebNov 4, 2024 · PCBP2 post-transcriptionally regulates sortilin expression by binding to a C-rich element in its 3' UTR. Embryos lacking the KH domain poly (C) binding protein, Pcbp2, are selectively deficient in the definitive erythroid lineage. Compared to wild-type controls, transcript splicing analysis of the Pcbp2 (-/-) embryonic liver reveals accentuated ...

WebGene ID: 128047921, updated on 28-Feb-2024. Summary Other designations. poly(rC)-binding protein 2 WebSingle-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:7607214, PubMed:12414943). Major cellular poly(rC)-binding protein …

WebFeb 28, 2024 · The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5´ 19 untranslated region (UTR), but its importance in the viral life cycle has remained unclear. 20 Herein, we aimed to clarify the role of PCBP1 in the HCV life cycle.

WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … chip referralWebPoly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 … chip referral codeWebRationale: Proper development of the heart relies on a tightly regulated, yet diverse, pattern of gene expression that is governed by transcriptional, post-transcriptional, and translational processe grapetree winchesterWebMar 19, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several ... chi prefab homesWebJul 4, 2024 · Previous studies have shown that poly (rC) binding protein 2 (PCBP2) belonging to a class of proteins that bind to poly (C) stretches of both RNA and DNA, recruits HECT-domain–containing E3 ... chip referral formWebAug 5, 2016 · 4. Discussion. Poly(rC) binding protein 2 (PCBP2, also called hnRNP E2 or α-CP2) belongs to the hnRNP-E family of RNA binding proteins that interact with a sequence-specific motif having single-stranded poly(C) tracts. PCBP2 contains a characteristic triple repeat of heterogeneous nuclear ribonucleoprotein K homology (KH)-domain. grape tree vacation rentals tortolaWebPoly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.. This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular … grapetree windsor